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2017
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  Journal of Medicine, Radiology, Pathology & Surgery (2017), No.6, Vol 4, November-December Issue  
 
Topic: Oral Cancer
Topic Editor: N/A
 
 
1 . CASE REPORT
Porphyria cutanea tarda - A case report
S. Muthu Kumar, B. Suman, K. R. Vijaylakshmi, C. Ramanna
Full Text PDF |   Abstract



ABSTRACT

Porphyria is a group of metabolic disorder that results due to decrease in uroporphyrinogen decarboxylase activity. A 64-year-old male patient presented to our department with a chief complaint of ulcer in lower lip for a week. Intraoral examination revealed a healing ulcer in lower lip with petechiae on the palate; general physical examination revealed multiple purpuric lesions over the upper and lower extremities predominantly involving the sun-exposed areas. The clinical features, histological findings with immunofluorescence test, and urine analysis confirmed the diagnosis of porphyria cutanea tarda. The details of which are discussed in this paper. Various primary cutaneous diseases involve the mucous membrane throughout the body, including oral mucosa. Hence, dentist must have sound knowledge to recognize and establish the diagnosis of the dermatosis exhibiting concomitant lesion of the oral mucosa.

Keywords: Photosensitivity, porphyria cutanea tarda, uroporphyrinogen decarboxylase

How to cite this article: Kumar SM, Suman B, Vijaylakshmi KR, Ramanna C. Porphyria cutanea tarda - A case report. J Med Radiol Pathol Surg 2017;4:1-3.

Received: 02 October 2017;

Accepted: 10 November 2017

 
2 . CASE REPORT
Poor prognosis of oral squamous cell carcinoma developing in young patient without habits along with perineural invasion - A case report with review of literature
Gopal Chandra Halder, Jay Gopal Ray
Full Text PDF |   Abstract



ABSTRACT

Vascular and lymphatic channels are well-established routes of metastatic spread of tumor cells from primary location to secondary site. However, another route of tumor spread is along nerves which have been described in several literatures since 1800AD. It is well accepted that perineural invasion (PNI) by tumor cells is a hallmark of poor prognosis and decreased survival rate. We are reporting a case of 28-year-old female without any deleterious oral habit complaining of pain and ulcer on the left lateral side of tongue for last 3 months. Regional lymph nodes were not palpable. Histopathological diagnosis was well differentiated squamous cell carcinoma (SCC) with PNI. The patient died within 5 months after diagnosis. Surgery was not performed due to rapid deterioration of general health. SCC of tongue in young patients without any habit showing PNI is essentially an aggressive lesion. This case report outlines the important issues pertaining to treatment planning of such patients.

Keywords: Perineural invasion, squamous cell carcinoma, tongue, without any habits

How to cite this article: Halder GC, Ray JG. Poor prognosis of oral squamous cell carcinoma developing in young patient without habits along with perineural invasion - A case report with review of literature. J Med Radiol Pathol Surg 2017;6:1-8.

Received: 02 October 2017;

Accepted: 10 November 2017

 
3 . CASE REPORT
Oral lichenoid reaction in association with amalgam fillings: A case report
Nanda G. Pai, Mahrokh F. Irani, Rajiv Desai
Full Text PDF |   Abstract



ABSTRACT

Oral lichenoid reactions (OLRs) are Type IV hypersensitivity reactions and most commonly seen in the buccal mucosa in close contact with amalgam restorations. They are often misdiagnosed causing months of pain and discomfort to the patient when they can be simply managed by removal of the offending amalgam restoration and replacing it with an intermediate one. This case aims to highlight one such case of OLR which was completely resolved on replacing amalgam with glass ionomer cement.

Keywords: Dental amalgam, lichen planus, Oral lichenoid reaction

How to cite this article: Pai NG, Irani MF, Desai R. Oral Lichenoid Reaction in Association with Amalgam Fillings: A Case Report.. J Med Radiol Pathol Surg 2017;6:1-15.

Received: 17 July 2017;

Accepted: 16 August 2017

 
4 . CASE REPORT
Florid keratin pearls in pleomorphic adenoma - A mimicker to malignancy
S. V. Sreelatha, Jagdish Chandra, B. Dhivya Bharathi
Full Text PDF |   Abstract



ABSTRACT

The presence of numerous keratin pearls on microscopic study is a feature commonly seen in well-differentiated squamous cell carcinoma. Pleomorphic adenoma (PA) can show the presence of squamous metaplasia with keratin pearls as a rare finding. Here, we present a case of a male patient in the 5th decade presenting with a mass on the buccal mucosa who smokes tobacco. On microscopic study, the mass showed tumor cells presenting with extensive keratin pearl formation. In this paper, we want to highlight the rare findings of extensive keratin in PA of minor salivary glands, the significance of special stains in diagnosis and differential diagnosis of this uncommon presentation.

Keywords: Cyst containing keratin, keratin pearls, minor salivary glands, myoepithelial cells, pleomorphic adenoma, squamous metaplasia

How to cite this article: Sreelatha SV, Chandra J, Bharathi BD. Florid keratin pearls in pleomorphic adenoma - A mimicker to malignancy. J Med Radiol Pathol Surg 2017;6:16-19.

Received: 15 October 2017;

Accepted: 21 November 2017

 
5 . CASE REPORT
Spindle cell embryonal rhabdomyosarcoma mimicking innocuous lesion – A case report
S. Muthu Kumar, B. Suman, K. R. Vijaylakshmi, C. Ramanna
Full Text PDF |   Abstract



ABSTRACT

Rhabdomyosarcomas (RMSs) are rare malignant neoplasms that originate from the embryonal cells called rhabdomyoblasts. Hence, they tend to be much more common in children, although rarely occurring in adults. A 19-year-old adult female patient reported with a complaint of painful growth in the lower anterior jaw. The patient gave a history of growth in the lower anterior labial vestibule 2 months ago which was insidious in onset and was first noticed 2 months ago for which patient had visited a private dental hospital where it was excised, records of which were not traceable. The clinical features with radiological, histopathological, and immunohistochemical findings confirmed the diagnosis of spindle cell embryonal RMS (ERMS) which are discussed in this paper in detail. Early diagnosis plays a pivotal role in the prognosis of spindle cell ERMS which is a fatal, rapidly proliferating, and malignant neoplasm. A thorough knowledge of the pathognomonic presentation of RMS can aid in differentiating from various innocuous soft tissue growths. Hence, the oral physician plays a key role in prompt diagnosis of such lesions which ensures better prognosis.

Keywords: Immunomarkers, Rhabdomyosarcoma, Spindle cell embryonal rhabdomyosarcoma

How to cite this article: Kumar SM, Suman B, Vijaylakshmi KR, Ramanna C. Spindle cell embryonal rhabdomyosarcoma mimicking innocuous lesion - A case report. J Med Radiol Pathol Surg 2017;4:1-4

Received: 05 October 2017;

Accepted: 29 November 2017

 
6 . CASE REPORT
Rubinstein–Taybi syndrome: A pediatric case report
Mridula Goswami, Ankita Verma
Full Text PDF |   Abstract



ABSTRACT

To describes the etiology and clinical features of Rubinstein-Taybi syndrome (RTS) which are important for the dental clinicians for the management of such cases. RTS also called as broad thumb-hallux syndrome is a genetic disorder which is characterized by orodental problems, growth retardation, facial dysmorphism, eye abnormalities, mental deficiency, kidney and heart ailments, and obesity. RTS is a rare congenital syndrome that occurs in one in 125,000 individuals. Mutations in two genes, i.e., cAMP-regulated enhancer binding protein and EP300 have been identified to cause RTS. Extraoral features reveal slanting palpebral fissures, broad forehead, broad nasal bridge, hypertelorism, and beaked nose. Intraoral features are small mouth opening, missing permanent teeth, high-arched narrow palate, malocclusion, and associated dental caries with gingival disease. Multidisciplinary collaboration is crucial for effective management and for well-being of the affected person.

Keywords: Broad thumb-hallux syndrome, mental deficiency, mutations

How to cite this article: Mridula Goswami, Ankita Verma. Rubinstein-Taybi syndrome: A pediatric case report. J Med Radiol Pathol Surg 2017;6:1-11.

Received: 01 October 2017

Accepted: 18 November 2017

 
 
     
 
   
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