Journal of Medicine, Radiology, Pathology & Surgery (2017), No.2, Vol 4, March-April Issue  
Topic: Oral Cancer
Topic Editor: N/A
Morphological variations of the coronoid process, condyle and sigmoid notch as an adjunct in personal identification
Tejavathi Nagaraj, Haritma Nigam, H. N. Santosh, Sita Gogula, C. K. Sumana, Poonam Sahu
Full Text PDF |   Abstract


Aim: To assess different morphological disparities of the coronoid process, the condyle and the sigmoid notch and their correlation with age and gender using panoramic radiographs for personal identification among the population in North Bengaluru.

Materials and Methods: The study was conducted using 300 digital orthopantomographs were examined for the different shapes of coronoid, condyle and sigmoid notch. Stratified sampling was done according to age intervals, side, and gender and the data obtained were subjected to statistical analysis, Chi-square test was done to evaluate the P value which was ascertained to be significant if <0.05.

Results: This study has illustrated various morphological shapes of the three selected entities and the most common shape of the coronoid process was observed to be triangular and that of sigmoid notch was the wider form. Whereas, the condylar shape commonly observed among the males and females were angled and round shapes, respectively. These variations when compared on both the sides had shown no statistical significance.

Conclusion: Various morphological shapes of coronoid process, condyle, and sigmoid notch are useful in anthropological studies and forensic dentistry. This study shows that the morphological variation using panoramic radiography can uncertainly be used as a screening method for personal identification due to its easy availability and suitability.

Keywords: Condyle, coronoid, sigmoid

How to cite this article: Nagaraj T, Nigam H, Santosh HN, Gogula S, Sumana CK, Sahu P. Morphological variations of the coronoid process, condyle and sigmoid notch as an adjunct in personal identification. J Med Radiol Pathol Surg 2017;4:1-5.

Received: 18 January 2017;

Accepted: 26 February 2017

Alcohol-medication interactions: A review
Tejavathi Nagaraj, Swati Saxena, Poonam Sahu, Arundhati Biswas, Haritma Nigam
Full Text PDF |   Abstract


Some medications when taken with alcohol cause accumulation of acetaldehyde by inhibiting aldehyde dehydrogenase (ALDH) enzyme. Acetaldehyde causes toxic effects in the body which are characterized by nausea, vomiting, facial flushing, hypotension and tachycardia, symptoms known as disulfiram-like reactions/antabuse effects or acetaldehyde syndrome. Alcohol interacts with many medications, thereby altering the metabolism of medications and/or alcohol. Alcohol dependence is an increasing and pervasive issue in today’s world. Withdrawal symptoms of alcohol are because of dependence syndrome and are seen mostly in hospitals. The signs and symptoms of alcohol withdrawal syndrome can be mild to severe. The severe and complicated alcohol withdrawal may manifest as seizures, hallucinations and delirium tremens. This article aims to review various alcohol-medication interactions.

Keywords: Alcohol medications interaction, alcohol withdrawal syndrome, antabuse, disulfiram reaction, fetal alcohol syndrome

How to cite this article: Nagaraj T, Saxena S, Sahu P, Biswas A, Nigam H. Alcohol-medication interactions: A review. J Med Radiol Pathol Surg 2017;4:6-9.

Received: 21 February 2017;

Accepted: 28 March 2017

A novel therapy of mycophenolate mofetil in the treatment of severe lichen planus: A review of literature
Keerthi Irugu, Tejavathi Nagaraj, Lakshmi Balraj, R. Shruthi, C. K. Sumana
Full Text PDF |   Abstract


Lichen planus (LP) is a mucocutaneous disease with varied clinical appearances. Although the exact etiology is unknown, activated T cells are mainly involved in the etiopathogenesis of LP. It is often a debilitating disease, and the treatment is aimed at palliation rather than cure. Similar histologic features are seen in both LP and graft versus host disease. Since etiological and histological features are similar in these diseases, mycophenolate mofetil has been tried to treat both these disorders.

Keywords: Debilitating, graft versus host disease, lichen planus, mycophenolate mofetil

How to cite this article: Irugu K, Nagaraj T, Balraj L, Shruthi R,

Sumana CK. A novel therapy of mycophenolate mofetil in the treatment of severe lichen planus: A review of literature. J Med Radiol Pathol Surg 2017;4:10-12.

Received: 11 February 2017;

Accepted: 23 March 2017

Sericin, a dietary additive: Mini review
Snehashish Ghosh, Roopa S. Rao, K. Shwetha Nambiar, Vanishri C. Haragannavar, Dominic Augustine, S. V. Sowmya
Full Text PDF |   Abstract


Realization of the nutritive value of silk and silk protein sericin is essential to exploit its compatibility and value added potential. Sericin, a globular protein, obtained from cocoons, as a part of the refining process. It has a wide array of applications in food industry, pharmaceuticals, molecular biology, cosmetics, and textile industry. Dietary intake of sericin reduces the levels of serum cholesterols and triglyceride. Furthermore, exhibits antioxidant activity by inhibiting tyrosinase enzyme. The nutritive value of sericin is explored in countries such as Japan and China. Although sericin is exploited in India in cosmetic industry, textiles, and pharmaceutical industry, it has not been explored in the food industry. Sericin is a unique protein; its rate of production is high, as enormous amount of silk is generated in India and most goes for waste. Instead, it can be utilized into a dietary additive in the food industry. The aim of this review article is to highlight the nutritional benefits of sericin and how best it can be utilized in food industry as a dietary additive for the health benefits.

Keywords: Food, nutrition, sericin

How to cite this article: Ghosh S, Rao RS, Nambiar KS, Haragannavar VC, Augustine D, Sowmya SV. Sericin, a dietary additive: Mini review. J Med Radiol Pathol Surg 2017;4:13-17.

Received: 01 February 2017;

Accepted: 18 March 2017

Myoepithelioma of hard palate: A case report
Karpagaselvi Sanjai, Roopavathi Keshavaiah, Harish Kumar, Sindhumathi Jayaram
Full Text PDF |   Abstract


Myoepitheliomas (ME) are benign neoplasm originating from myoepithelial cells of seromucinous glands. Majority of these tumours arise in parotid gland followed by minor salivary glands of palate. The tumor does not show any unique clinicopathologic features that is different from other benign salivary gland tumors but is believed to have more aggressive behaviour. The histopathological patterns vary to very great extent and usually show overlapping features with other benign and malignant tumours. We report a case of 38-year-old male patient with a solitary swelling present on the right side of the hard palate. The histopathologic picture of the lesion showed spindle, plamacytoid and epitheliod cells. The connective stroma showed areas of hyalinization and keratin pearl formation making it difficult to differentiate from pleomorphic adenoma as well as its malignant counterpart. An Immunohistochemical analysis was done using S100, smooth muscle actin, Ki-67 and a definitive diagnosis of ME was made.

Keywords: Benign myoepithelial tumor, cellular pleomorphic adenoma, myoepithelial adenoma, myoepithelial carcinoma, myoepithelioma

How to cite this article: Sanjai K, Keshavaiah R, Kumar H, Jayaram S. Myoepithelioma of hard palate: A case report. J Med Radiol Pathol Surg 2017;4:18-21.

Received: 14 February 2017;

Accepted: 12 March 2017

Bilateral osteoradionecrosis of the jaw – A rare case report
Tejavathi Nagaraj, Haritma Nigam, Arundhati Biswas, Sita Gogula
Full Text PDF |   Abstract


Osteoradionecrosis (ORN) is among the extensive and most solemn oral complications of radiotherapy of head and neck malignancies with a tardy radiation-induced injury, occurring most commonly in mandible with the most striking features of necrosis of bone and its failure to heal. Unlike other complications, the exact etiology of its occurrence, risk factors are not known, but the theory of hypoxia, hypovascularity, and hypocellularity is considered to be the most widely accepted theory till now. This article presents a clinical case of bilateral ORN of the mandible, occurring with exposed and infected bone, necrotic process that extended through body of the mandible and traumatic extraction was considered to be the etiology of exposed bone. Due to the stage of the condition, a decision for surgical treatment accompanied with antibiotics was made. Proper oral hygiene and frequent dental checks ups should be performed by irradiated patients and patients with osteoradionecrosis.

Keywords: Mandible, osteoradionecrosis, radiotherapy

How to cite this article: Nagaraj T, Nigam H, Biswas A, Gogula S. Bilateral osteoradionecrosis of the jaw - A rare case report. J Med Radiol Pathol Surg 2017;4:22-2.6

Received: 01 February 2017;

Accepted: 18 March 2017

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