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  Journal of Medicine, Radiology, Pathology & Surgery (2017), No.1, Vol 4, January-February Issue  
 
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1 . REVIEW ARTICLE
Role of ascorbic acid in diabetes mellitus: A comprehensive review
H. N. Santosh, Chaya M. David
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ABSTRACT

Diabetes mellitus (DM) is a multifactorial disease with no one specifi c drug available to treat. Th e main causes of DM Type 2 are insulin resistance and decreased insulin production. Oxidative damage to beta cells due to reactive oxygen species is a trusted cause of DM2. Vitamins are a class of nutrients required in miniscule quantity. Vitamin C is one of the most powerful dietary antioxidant available, closest in structure to carbohydrate. Vitamin C and glucose competitively inhibit each other to penetrate the cell membrane by the tunneling mechanism. Clinical trials have suggested that mega doses of vitamin C reduce the microvascular complications of DM2 such as retinopathy, nephropathy, and diabetic foot. Apart from this, there is another biological signifi cance of vitamin C. Vitamin C in higher dose reduces the (glycosylated hemoglobin concentration) levels and low-density lipoproteins. Role of vitamin C as an adjunct in the treatment of DM2, atherosclerosis has been signifi cantly contributory. Th is review paper presents the diff erent biological roles of vitamin C, in particular DM2.

Keywords: Diabetes mellitus, oxidative stress, reactive oxygen species, vitamin C

How to cite this article: Santosh HN, David CM. Role of ascorbic acid in diabetes mellitus: A comprehensive review. J Med Radiol Pathol Surg 2017;4:1-3.

Received: 10 December 2016;

Accepted: 28 February 2017

 
2 . REVIEW ARTICLE
Nanotechnology – Paving way for modern dentistry
Lakshmi Balraj, Tejavathi Nagaraj, Keerthi Irugu, R. Shruthi
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ABSTRACT

Nanotechnology is the evolutionary science that deals with the physical, chemical, and biological properties of matter at nanoscale dimensions. It has proven to hold a great promise in the field of advanced diagnostics and targeted drug delivery. Dentistry is now undergoing a great deal of transformation into nanodentistry for the betterment of mankind. However, nanotechnology has become a controversial issue due to insufficient evidence on potential hazards on human health and environment. The present article throws light on the present scenario and the future implications of nanodentistry.

Keyword: Nanodentistry, nanomedicine, nanotechnology

How to cite this article: Balraj L, Nagaraj T, Irugu K, Shruthi R. Nanotechnology – Paving way for modern dentistry. J Med Radiol Pathol Surg 2017;4:4-6.

Received: 21 December 2016;

Accepted: 28 January 2017

 
3 . CASE REPORT
Traumatic bone cyst of the jaws: An idiopathic entity
Tejavathi Nagaraj, Haritma Nigam, Swati Saxena, C. K. Sumana
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ABSTRACT

The synonym for traumatic bone cyst (TBC) is solitary bone cyst, idiopathic bone cyst and is characterized as the presence of infectious bony cavity fi lled with fl uid and litt le quantities of tissue with no lining of epithelium. Typically these lesions show no symptoms and are detected coincidently while performing routine radiographic investigation for another purpose for which the patient reported. Usually, these cavities are found to be empty but occasionally may contain serosanguinous fl uid, clots, erythrocytes, fi brin, and giant cells. Of the jaw bones, this cyst is preferentially found more in the mandible than in maxilla. In this report, we present a case of asymptomatic TBC in the anterior mandible.

Keywords: Idiopathic bone cyst, mandible, maxilla, traumatic bone cyst

How to cite this article: Nagaraj T, Nigam H, Saxena S, Sumana CK. Traumatic bone cyst of the jaws: An idiopathic entity. J Med Radiol Pathol Surg 2017;4:7-10.

Received: 05 January 2017;

Accepted: 27 February 2017

 
4 . CASE REPORT
Erosive lichen planus: A case report
Lakshmi Balraj, Tejavathi Nagaraj, Haritma Nigam, Sida Tagore
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ABSTRACT

Lichen planus (LP) is a chronic infl ammatory autoimmune mucocutaneous disease aff ecting about 2% of the population. Th ere are three basic forms of oral LP (OLP) which includes hypertrophic, erythematous, and bullous forms. Th e erosive form is the second most common form of OLP following the reticular type. Th is case report reviews the clinical approach to an erosive variant of OLP; wherein, the patient was educated, counseled about the chronicity of the condition and also about its high risk of malignant transformation; immediate biopsy being prompted; followed by the institution of appropriate, timely treatment.

Keywords: Erosive lichen planus, topical corticosteroids, triamcinolone acetonide

How to cite this article: Balraj L, Nagaraj T, Nigam H, Tagore S. Erosive lichen planus: A case report. J Med Radiol Pathol Surg 2017;4:11-14.

Received: 22 December 2016

Accepted: 28 January 2017

 
5 . CASE REPORT
Irritational fi broma of gingiva in a young female: A case report
Kirti Saharan, S. Shivaprasad, R. Poornima, L. Ashok
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ABSTRACT

Irritational fibroma is a reactive lesion that is among the most common oral soft -tissue lesions, caused due to local trauma or irritation by plaque, calculus, overhanging margins, and restorations. It is most commonly seen on buccal mucosa along the line of occlusion in third to fourth decade of life. the second most common site is the maxillary anterior gingiva. The color is usually same as the surrounding mucosa and consistency is soft to firm. This paper aims to present a rare case of irritational fibroma of gingiva in a 15-year-old adolescent female patient.

Keywords: Gingiva, irritational fibroma, trauma, young female

How to cite this article: Saharan K, Shivaprasad S, Poornima R, Ashok L. Irritational fibroma of gingiva in a young female: A case report. J Med Radiol Pathol Surg 2017;4: 15-17.

Received: 11 January 2017;

Accepted: 28 February 2017

 
6 . CASE REPORT
Midfacial paraesthesia - An unusual presentation in paranasal sinusitis
Swetha Paulose, Vishwanath Rangdhol, L. Kavya, V. L. Laxman
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ABSTRACT

Facial paraesthesia is seen in variety of disorders, usually arising due to nerve compression or damage. Maxillary sinus pathologies could potentially impact the infraorbital nerve, causing numbness of the midfacial region. A 52-year-old male presented with right side facial numbness of 20 days duration with history of chronic headache and upper respiratory tract infection. An inadvertent endodontic therapy had been performed earlier on maxillary right central incisor providing no relief. Right maxillary sinus was tender on palpation. Nasal endoscopy showed purulent collection in right maxillary sinus. Computerized tomography para-nasal sinuses revealed right maxillary, sphenoid, and ethmoid sinus involvement with cortical erosion of infra orbital foramen. Remission was found on antibiotic therapy. Clinicians should recognize the underlying causes responsible for unusual symptoms of chronic sinusitis and a unilateral facial numbness could be the result of bony erosion due to underlying pathology.

Keywords: Infra orbital nerve, maxillary sinus, mid-facial paraesthesia, rhinosinusitis

How to cite this article: Paulose S, Rangdhol V, Kavya L, Laxman VL. Midfacial paraesthesia - An unusual presentation in paranasal sinusitis. J Med Radiol Pathol Surg . J Med Radiol Pathol Surg 2017;4:18-21.

Received: 18 December 2016;

Accepted: 26 January 2017

 
 
     
 
   
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