Journal of Medicine, Radiology, Pathology and Surgery

1.EDITORIAL

Publication in a scientific journal of health science: Experience as an editor, reviewer, and an author

D. B. Nandini, M. G. Madhura, Roopa S Rao

[Year:2018] [Month:November-December] [Volume:5 ] [Number:6] [Pages No:1-2] [No. of Hits: 68]

  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jmrps.146]

ABSTRACT

Publication in health science journal has been visualized as one of the methods at health-care professional’s disposal to exhibit scientific talent to peer group. Frequent and successful publication of research brings laurels to the scholars as well as their institutions. The number of publications of a teacher/ scholar/health-care professional in an academic institution and university is used to measure individual’s competency. The present paper highlights the experiences of the authors from various perspectives such as an editor, reviewer, and an author.

How to cite this article: Nandini DB, Madhura MG, Rao RS. Publication in a scientific journal of health science: Experience as an editor, reviewer, and an author. J Med Radiol Pathol Surg 2018;5:1-2

Received: 19 September 2018;

Accepted: 18 October 2018

2.ORIGINAL ARTICLE

A revisit of cytological features in phyllodes tumors

K. R. Chatura, Thingujam Deeparani, S. B. Patil

[Year:2018] [Month:November-December] [Volume:5 ] [Number:6] [Pages No:3-8] [No. of Hits: 67]

  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jmrps.147]

ABSTRACT

Background: Phyllodes tumor (PT) and fibroadenoma (FA) share a common dimorphic pattern with both epithelial and stromal components. Fine-needle aspiration cytology (FNAC) is commonly used pre-operative investigation of palpable breast masses. However, it is less successful in the diagnosis of PT with sensitivity ranging from 32 to 77% and generally with high false negative rate.

Aims and Objectives: In an effort to improve the result of an already existing FNAC technique, we retrospectively studied smears from histologically proven cases of PT with the aim of defining cytological features that help in the diagnosis.

Materials and Methods: A total of 27 histologically diagnosed PTs from June 2016 to December 2018 were included. Cytological features reevaluated were number and cellularity of epithelial and stromal components and dispersed stromal cells in the background on FNAC for ensuring a diagnosis of PT.

Results: Seven cases were reported FA with epithelial predominance and lack of stromal components. 15 cases were diagnosed PT due to the appreciation of exaggerated stromal features. 3 were “inadequate” and 2 were “equivocal” on revised cytological diagnosis. Accuracy rate in pre-operative smears was 47.82% and reached 78.26% after a review. The Chi-square statistic is 4.023 and P = 0.0448 and significant at P < 0.05.

Conclusion: Distinction of PT from FA on FNAC becomes difficult due to overlapping features. Unfamiliarity with the cytological features due to disease rarity, morphological heterogeneity, and inadequate sampling might be the explanation for poor outcome with FNAC. These cytological parameters individually may not give encouraging results, but, taken together, can be used effectively in distinguishing the two groups as a pre-operative diagnosis of PT is crucial to plan for surgical treatment.

Keywords: Cyto-histo correlation, phyllodes tumor

How to cite this article: Chatura KR, Deeparani T, Patil SB. A revisit of cytological features in phyllodes tumors. J Med Radiol Pathol Surg 2018;5:3-8

Received: 21 September 2018;

Accepted: 24 October 2018

3.ORIGINAL ARTICLE

Comparison of clinical response and Doppler parameters after intracorporeal injection of vasoactive agents in erectile dysfunction

Venkateshwaran Arumugam, Lokesh Thanikavelu

[Year:2018] [Month:November-December] [Volume:5 ] [Number:6] [Pages No:9-12] [No. of Hits: 72]

  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jmrps.148]

ABSTRACT

Objective: The objective of this study was to compare the clinical response and Doppler parameters after intracorporeal injection of vasoactive agents in erectile dysfunction.

Materials and Methods: The hemodynamic function of the penis can be evaluated noninvasively by performing or power Doppler US with spectral analysis following injection of a vasoactive pharmacological agent papaverine, to induce an erection.

Results: we conclude that Doppler, color flow Doppler sonography yields a consistent waveform/pressure pattern that provides insight into the integrity of the arterial and venous sinusoidal erectile mechanisms, but it is not a sensitive tool defining the exact cause of subclinical response in a subset of cases.

Keywords: Doppler ultrasonography, erectile dysfunction, venous insufficiency

How to cite this article: Arumugam V, Thanikavelu L. Comparison of clinical response and Doppler parameters after intracorporeal injection of vasoactive agents in erectile dysfunction. J Med Radiol Pathol Surg 2018;5:9-12

Received: 11 October 2018;

Accepted: 24 November 2018

4.ORIGINAL ARTICLE

Efficacy of conservative versus intralesional therapy in OSMF – A comparative study

G. Shubha, R. Sheshaprasad, Pragathi Hebbar, Anuradha Pai, A. R. Shubhasini, G. Keerthi

[Year:2018] [Month:November-December] [Volume:5 ] [Number:6] [Pages No:13-17] [No. of Hits: 75]

  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jmrps.149]

ABSTRACT

Background and Objectives: Oral submucous fibrosis (OSMF) is a potentially malignant lesion of the oral cavity and successful management remains a challenge. Our study aims to compare the efficacy of three commonly used modalities of treatment, namely (i) non-invasive therapy like physiotherapy only, (ii) physiotherapy in combination with antioxidants, and (iii) invasive therapy like intralesional therapy. It aimed to ascertain the most effective treatment modality among the three which one of them helped improve the maximum mouth opening (MMO) and reduce oral sensitivity to spicy food as measured on numeric analog scale (NAS).

Materials and Methods: This randomized multilabel study was conducted on 49 patients visiting the outpatient Department of Oral Medicine and Radiology, over a 2-year period. A detailed history of burning sensation in the mouth and the severity was recorded using NAS. A Vernier caliper was used for the measurement of MMO. The symptom of burning sensation and MMO was evaluated on the 15th, 30th, 45th, and 90th days.

Results: Findings from the study showed that physiotherapy alone was not effective in alleviating neither burning sensation nor did it significantly improve the MMO. The percentage decrease in burning sensation was highest in the interventional group receiving an intralesional injection (87.4% at 45 days and 100% at 90 days). Physiotherapy with antioxidant group showed almost similar percentage decrease in burning sensation as the interventional group (80.8% at 45 days and 96.8% at 90 days. For MMO, physiotherapy with antioxidant group showed better MMO at 90 days (34.2% vs. 26.8%).

Conclusion: A non-invasive treatment modality of physiotherapy with antioxidant treatment modality is as effective as an invasive intralesional injection, in the management of patients with OSMF. The findings suggest that non-invasive modality of physiotherapy with antioxidant treatment can be considered as standard care for the management of OSMF.

Keywords: Burning sensation, Intralesional injection, Maximum mouth opening, Non-invasive therapy, Oral submucous fibrosis, Physiotherapy

How to cite this article: Shubha G, Sheshaprasad R, Hebbar P, Pai A, Shubhasini AR, Keerthi G. Efficacy of conservative versus intralesional therapy in OSMF - A comparative study. J Med Radiol Pathol Surg 2018;5:13-17

Received: 16 October 2018;

Accepted: 20 November 2018

5.REVIEW ARTICLE

Stem cell research: A new ray of hope

G. J. Renukaradhya, V. S. Shilpa, K. Shwetha Nambiar, Roopa S. Rao

[Year:2018] [Month:November-December] [Volume:5 ] [Number:6] [Pages No:18-20] [No. of Hits: 74]

  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jmrps.150]

ABSTRACT

Stem cell research has been gaining popularity across the globe in recent years with regenerative medicine that is involved in cloning and gene line engineering. The study of stem cell biology requires more human pluripotent and multipotent stem cells. As the stem cell biology varies in humans and mice, human stem cells are required. Citizens should participate in discussing ethical concerns and policy issues regarding stem cell research. There should be specific protocols to enhance production, survival, and integration of transplanted stem cells. This review discusses about the advantages, challenges of stem cell research with strategies to overcome the hurdles.

Keywords: Advantages, challenges, stem cells

How to cite this article: Renukaradhya GJ, Shilpa VS, Nambiar S, Rao RS. Stem cell research: A new ray of hope. J Med Radiol Pathol Surg 2018;5:18-20.

Received: 16 November 2018;

Accepted: 21 November 2018

6.CASE REPORT

Polymorphous low-grade adenocarcinoma of parotid gland – A case report and review

Sravya Guda, Anupama N. Kalapannavar, K. P. Mohan Kumar, S. Subha Lakshmi

[Year:2018] [Month:November-December] [Volume:5 ] [Number:6] [Pages No:21-23] [No. of Hits: 71]

  • [PDF]
  • [Abstract]
  • [DOI : 10.15713/ins.jmrps.151]

ABSTRACT

Polymorphous low-grade adenocarcinoma (PLGA) is a low aggressive tumor commonly occurring in minor salivary glands. Its occurrence is rarely documented in major salivary glands. Diagnosis of PLGA is challenging both clinically and histologically due to its slow-growing behavior. Here, we report a case of PLGA arising from the right parotid gland in a 48-year-old female patient.

Keywords: Parotid gland, pleomorphic adenoma, salivary gland neoplasm

How to cite this article: Guda S, Kalapannavar AN, Kumar KPM, Lakshmi SS. Polymorphous low-grade adenocarcinoma of parotid gland - A case report and review. J Med Radiol Pathol Surg 2018;5:21-23.

Received: 21 November 2018;

Accepted: 20 December 2018