Journal of Medicine, Radiology, Pathology and Surgery

Current Issue (Vol 6, NO. 1, January-February 2019 Issue)

NARRATIVE REVIEW

M. G. Madhura, Lipika Kansal, B. Veerendra Kumar

Cancer stem cell markers in oral squamous cell carcinoma – Revisited

Year:2019 | Month:January-February | Volume:6 | Number:1 | Pages No:1-3



Cancer tissue is heterogeneous in its cellular population comprising various cell types; cancer stem cells (CSCs) are a small component of it. CSCs have the ability of self-sustainability and result in heterogeneous lineages. CSCs form a crucial component as they are involved in progression, metastasis, recurrence, and chemoresistance. Numerous CSC markers have been studied in a variety of neoplasms in humans including oral squamous cell carcinoma (OSCC). Here is a quick overview of various CSC markers and their role in head-and-neck cancer and/OSCC.

Keywords: Aldehyde dehydrogenase, Bmi-1, Cancer stem cells, CD44, CD133, c-Met, Klf-4, Lgr5, Oral squamous cell carcinoma

How to cite this article: Madhura MG, Kansal L, Kumar BV. Cancer stem cell markers in oral squamous cell carcinoma - Revisited. J Med Radiol Pathol Surg 2019;6:1-3.

Received: 02 November 2018;

Accepted: 26 December 2018


REVIEW ARTICLE

Snehashish Ghosh, Roopa S. Rao, K. Shwetha Nambiar, Vanishri C. Haragannavar, Dominic Augustine, S. V. Sowmya

Sericin, a dietary additive: Mini review

Year:2019 | Month:January-February | Volume:6 | Number:1 | Pages No:4-8



Realization of the nutritive value of silk and silk protein sericin is essential to exploit its compatibility and value added potential. Sericin, a globular protein, obtained from cocoons, as a part of the refining process. It has a wide array of applications in food industry, pharmaceuticals, molecular biology, cosmetics, and textile industry. Dietary intake of sericin reduces the levels of serum cholesterols and triglyceride. Furthermore, exhibits antioxidant activity by inhibiting tyrosinase enzyme. The nutritive value of sericin is explored in countries such as Japan and China. Although sericin is exploited in India in cosmetic industry, textiles, and pharmaceutical industry, it has not been explored in the food industry. Sericin is a unique protein; its rate of production is high, as enormous amount of silk is generated in India and most goes for waste. Instead, it can be utilized into a dietary additive in the food industry. The aim of this review article is to highlight the nutritional benefits of sericin and how best it can be utilized in food industry as a dietary additive for the health benefits

Keywords: Food, nutrition, sericin

How to cite this article: Ghosh S, Rao RS, Nambiar KS, Haragannavar VC, Augustine D, Sowmya SV. Sericin, a dietary additive: Mini review. J Med Radiol Pathol Surg 2019;6:4-8.

Received: 02 November 2018;

Accepted: 26 December 2018


CASE REPORT

D. B. Nandini, N. B. Nagaveni, B. S. Deepak, P. Poornima

Bilateral dens evaginatus in deciduous first molars: A rare finding

Year:2019 | Month:January-February | Volume:6 | Number:1 | Pages No:9-11



Dens evaginatus is a developmental anomaly affecting the shape of the teeth. Although many cases have been reported in permanent dentition, the occurrence in deciduous dentition is rare. Although the condition does not cause serious consequences, sometimes it may result in problems necessitating professional treatment. This article reports a rare case of bilateral dens evaginatus in deciduous mandibular first molar. A brief review of etiology, complications, preventive measures, and management has been discussed.

Keywords: Accessory cusp, deciduous dentition, dens evaginatus, evaginated odontoma, occlusal enamel pearl, primary mandibular molar, supernumerary cusp, talon’s cusp, tubercle

How to cite this article: Nandini DB, Nagaveni NB, Deepak BS, Poornima P. Bilateral dens evaginatus in deciduous first molars: A rare finding. J Med Radiol Pathol Surg 2019;6:9-11.

Received: 10 November 2018;

Accepted: 15 December 2018


CASE REPORT

B. M. Kavya, G. M. Revanna, H. C. Girish, Sanjay Murgod

Synodontism involving both primary and permanent teeth in a mixed dentition case

Year:2019 | Month:January-February | Volume:6 | Number:1 | Pages No:12-14



Fusion is a sort of developmental alteration due to the union of 2 adjacent tooth buds. It can be either partial or complete fusion, depending on the stage of tooth development. It can occur in either deciduous or permanent dentition. Here, we report a rare case of fusion in both deciduous and permanent teeth that are in between deciduous maxillary central and lateral incisors and in between permanent mandibular central and lateral incisors in a 10-year-old boy.

Keywords: Bifid teeth, connated teeth, developmental disturbance, double teeth, fusion, synodontism

How to cite this article: Kavya BM, Revanna GM, Girish HC, Murgod S. Synodontism involving both primary and permanent teeth in a mixed dentition case. J Med Radiol Pathol Surg 2019;6:12-14.

Received: 20 November 2018;

Accepted: 26 December 2018


CASE REPORT

A. N. Sulabha, Nikhat M. Attar, Mohammed Arif M. Awati, G. Suchitra

Erupted odontoma mimicking peg lateral incisor associated with impacted maxillary lateral incisor and canine – A rare clinical case report

Year:2019 | Month:January-February | Volume:6 | Number:1 | Pages No:15-17



Odontomas are the most common benign tumors of odontogenic origin. They are often asymptomatic, accidently discovered in routine radiograph and may interfere in eruption of associated teeth. Rarely, they erupt in the oral cavity. We present an unusual case report of partially erupted compound odontoma mimicking peg lateral incisor in the region of clinically missing maxillary lateral incisor, associated with impacted lateral incisor and canine. Erupted odontoma in anterior region associated with impacted permanent teeth may compromise dental and facial esthetics and, therefore, requires appropriate treatment.

Keywords: Compound odontoma, erupted odontoma, impacted permanent teeth

How to cite this article: Sulabha AN, Attar NM, Awati MAM, Suchitra G. Erupted odontoma mimicking peg lateral incisor associated with impacted maxillary lateral incisor and canine - A rare clinical case report. J Med Radiol Pathol Surg 2019;6 :15-17.

Received: 12 November 2018;

Accepted: 29 December 2018


CASE REPORT

Kaushik Ranjan Deb, D. B. Nandini, Koijam Sashikumar Singh

Oral squamous papilloma in a pediatric patient: A case report and review

Year:2019 | Month:January-February | Volume:6 | Number:1 | Pages No:18-21



Squamous papillomas are benign exophytic lesions that are commonly found in the oral cavity. Although the exact etiology of the lesion is not known, an association with human papillomavirus (HPV) infection is suggested. On the contrary, some recent studies have showed no correlation between HPV and squamous papilloma. This article presents a case of 4-year-old male patient who reported with a papillary lesion on the palatal gingival which was diagnosed as oral squamous papilloma by histopathologic examination.

Keywords: Clinical features, diagnosis, etiology, histopathology, human papillomavirus, koilocytes, pediatric patient, squamous papilloma

How to cite this article: Deb KR, Nandini DB, Singh KS. Oral squamous papilloma in a pediatric patient: A case report and review. J Med Radiol Pathol Surg 2019;6:18-21.

Received: 12 December 2018;

Accepted: 29 January 2019